| Title | [The determination of medical reference values for tumor markers in cerebrospinal fluid.] | | Author(s) | Shi Q, Pu CQ, Wu WP, Huang XS, Yu SY, Tian CL, Cao XT | | Institution | Department of Neurology, Department of medical statistics General Hospital of PLA, Beijing 100853, China. | | Source | Zhonghua Yi Xue Za Zhi 2009 Feb 10; 89(5):355-6. | | Abstract | OBJECTIVE: To determine medical reference values for tumor markers in cerebrospinal fluid.
METHODS: Concentrations of CEA, CA125, CA15-3, CA19-9, CA72-4, CYFRA21-1, AFP, NSE, SCC and HCG were determined by means of double-antibody sandwich ELISA in 110 patients excluding primary tumors and meningeal carcinomatosis using Roche E170 modular immunoassay analyzer.
RESULTS: The determined medical reference values for tumor biomarkers in cerebrospinal fluid were as follows: CEA < 0.573 microg/L, CA125 < 2.591 U/ml, CA15-3 < 2.045 U/ml, CA19-9 < 2.272 U/ml, CA72-4 < 1.252 U/ml, CYFRA21-1 < 1.44 ng/ml, AFP < 0.968 microg/L, NSE < 57.666 ng/ml, SCC < 0.5 microg/L, HCG < 0.769 U/L. There was no correlation between any tumor marker and age (P > 0.05). Concentrations of tumor markers were not affected by gender (P > 0.05).
CONCLUSION: Medical reference values for CEA, CA125, CA15-3, CA19-9, CA72-4, CYFRA21-1, AFP, NSE, SCC and HCG in cerebrospinal fluid were first determined. | | Language | chi | | Pub Type(s) | English Abstract
Journal Article
| | PubMed ID | 19563718 |
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